The medical guidelines for childhood LCH have been published in Pediatric Blood & Cancer  (PBC), Wiley Online Library.

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» Expert Histio Net » For Professionals » Guidelines » LCH childhood » Methods / Development  · 

Methods and Process of development

Author(s): Euro Histio Net Work Group for LCH Guidelines (see introduction page), Created: 2011/03/09, last update: 2012/07/26

These guidelines were designed and established by an international group of physicians who have been involved in the study and management of histiocytic disorders for several years. They are active members of the international medical society of histiocytoses “Histiocyte Society” (HS), of the European national societies of Hematology/Oncology, and of their respective national groups for the study and treatment of these diseases. Drafts were commented by the entire group and redrafted by the guidelines editor. Final agreement was consensual.

In summary, the following guidelines are an adaption of different international and national guidelines and recommendations documents:

  • Langerhans Cell Histiocytosis – Evaluation and Treatment Guidelines of the Histiocyte Society
  • LCH – Recommendations for therapeutic care of Langerhans Cell Histiocytosis, French Study Group for Histiocytosis of the French Society for Pediatric Haematology and Immunology (SHIP) and the French Society for Children’s and Adults’ Cancer and Leukemia (SFCE)
  • Langerhans Cell Histiocytosis (LCH) – Guidelines for Diagnosis and Therapy in Paediatric Haematology and Oncology, developed by the Histiocyte Society and the German Society for Paediatric Oncology and Haematology (GPOH) for the German Study Group for the Scientific Medical Societies (AWMF)

The contents of these documents were systematically reviewed and updated where new evidence was available in scientific articles published in peer-reviewed journals in the years till 2010.