Follow-up - Required Tests and Frequency

Author(s): Euro Histio Net Work Group for LCH Guidelines (see introduction page), Created: 2011/05/21, last update: 2012/01/23


Tab. 7. Recommendations for follow-up of patients with LCH


Group of Patients	Test	Frequency
All Patients	Clinical assessment	End of therapy Every clinc visit
	Height, Weight, Pubertal status	End of therapy Every 6 months until final height is achieved
	History of thirst, polyuria	Every clinic visit
	Neurological assessment	Every clinic visit
With involvement of bone (axial skeleton and/or limbs)	Orthopaedic assessment	End of therapy Yearly until completion of pubertal growth
With involvement of ear, mastoid and skull base	Audiometry or Audiometry Evoked Responses in younger children	End of therapy Before entering school If symptoms develop
With involvement of oral tissue and jaw	Dental assessment	Yearly
CNS positive or with involvement of skull base (orbital lesions, DI, anterior pituitary deficiency)	Neuropsychometric assessment	End of therapy Every 1 - 2 years
	Cerebral MRI (details see here)	End of therapy
With involvement of lungs	Spirometry	End of therapy Every 6 months for 2 years Every year for 10 yerars
With involvement of liver	Sonography	End of therapy
	Bilirubin, γGT, Alkaline phosphatase	End of therapy